Anti-Ctip1/BCL-11A Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Fornitore: Bioss
BOSSBS-11544R-A488EA 858 EUR
Anti-Ctip1/BCL-11A Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Bcl-11a genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: Ctip1/BCL-11A
Clonality: Polyclonal
Conjugation: Alexa Fluor® 488
Host: Rabbit
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