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Anti-HOXA6 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Fornitore: Bioss
BOSSBS-11294R-A350EA 858 EUR
BOSSBS-11294R-A350
Anti-HOXA6 Rabbit Polyclonal Antibody (Alexa Fluor® 350)
Anticorpi
The Hox homeobox genes encode proteins that are transcriptional regulators with an established role in embryonic development. HoxA6 (homeobox A6), also known as HOX1B, is a 233 amino acid protein that localizes to the nucleus. Expressed during embryonic development, HoxA6 functions as a sequence-specific DNA-binding transcription factor that is part of a regulatory mechanism that provides cells with positional identities during development. Via its ability to bind DNA, HoxA6 plays an important role in the regulation of gene expression, as well as morphogenesis and differentiation. The gene encoding HoxA6 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: HOXA6
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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