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Anti-EVC Rabbit Polyclonal Antibody (Cy5®)

Fornitore: Bioss
BOSSBS-11282R-CY5EA 858 EUR
BOSSBS-11282R-CY5
Anti-EVC Rabbit Polyclonal Antibody (Cy5®)
Anticorpi
EVC is an autosomal skeletal dysplasia caused by mutations in the EVC and EVC2 genes. Found in developing ribs, heart, kidney and lung, the EVC gene is responsible for normal development of the face, limbs, teeth and nails. The protein expressed by the EVC gene is an intracellular component of the hedgehog signal pathway that contains a leucine zipper and transmembrane domain. Defects in the EVC gene can lead to short-limb dwarfism, ectodermal dysplasia and cardiac anomalies such as irregular atrioventricular septum development. Additionally, the EVC gene has been implicated in Weyers acrodental dysostosis, an autosomal dominant disease characterized by facial abnormalities and limb defects.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: EVC
Clonality: Polyclonal
Clone:
Conjugation: Cy5®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
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