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Anti-WFS1 Rabbit Polyclonal Antibody (Cy3®)

Fornitore: Bioss
BOSSBS-11272R-CY3EA 858 EUR
BOSSBS-11272R-CY3
Anti-WFS1 Rabbit Polyclonal Antibody (Cy3®)
Anticorpi
Wolfram syndrome protein (WFS1) is an 890 amino acid protein that contains a cytoplasmic N-terminal domain, followed by nine-transmembrane domains and a luminal C-terminal domain. WFS1 is predominantly localized to the endoplasmic reticulum (ER) (1) and its expression is induced in response to ER stress, partially through transcriptional activation (2,3). Research studies have shown that mutations in the WFS1 gene lead to Wolfram syndrome, an autosomal recessive neurodegenerative disorder defined by young-onset, non-immune, insulin-dependent diabetes mellitus and progressive optic atrophy (4).

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: WFS1
Clonality: Polyclonal
Clone:
Conjugation: Cy3®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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