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Anti-DERL1 Rabbit Polyclonal Antibody (Cy3®)

Fornitore: Bioss
BOSSBS-11268R-CY3EA 858 EUR
BOSSBS-11268R-CY3
Anti-DERL1 Rabbit Polyclonal Antibody (Cy3®)
Anticorpi
Degradation in endoplasmic reticulum proteins, also designated Derlins or DERtrins, are crucial for the degradation of misfolded endoplasmic reticulum (ER) luminal proteins. Derlin proteins are multi-pass membrane proteins localizing to the ER. Derlins are involved in transferring misfolded proteins from the ER to the cytosol, where the misfolded proteins are destroyed in an ubiquitin-dependent manner by the proteasome. In the case of cytomegalovirus infection, Derlin-1, as opposed to Derlins-2 and -3, is involved in the export of MHC class I heavy chains from the ER via its interaction with the viral protein US11. Derlins may also be important for cell proliferation.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: DERL1
Clonality: Polyclonal
Clone:
Conjugation: Cy3®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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