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Anti-NSF Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Fornitore: Bioss
BOSSBS-11255R-FITCEA 858 EUR
BOSSBS-11255R-FITC
Anti-NSF Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Anticorpi
Several protein-protein interactions are essential to membrane fusion during endocytosis. Membrane fusion requires interaction among SNARE1 proteins associated with both donor and acceptor membranes (1,2). Following membrane fusion, the α-SNAP cytoplasmic adapter protein binds to the SNARE complex. N-ethylmaleimide-sensitive factor (NSF), a hexameric ATPase, then associates with the α-SNAP/SNARE complex to mediate SNARE disassembly during membrane fusion (3,4). The ATPase activity of NSF induces a conformational change in the α-SNAP/SNARE complex that leads to its dissociation from the membrane, membrane fusion and eventual recycling of the SNARE complex for subsequent membrane fusion (3,4).

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: NSF
Clonality: Polyclonal
Clone:
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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