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Anti-SEMA4C Rabbit Polyclonal Antibody (Cy7®)

Fornitore: Bioss
BOSSBS-1123R-CY7EA 858 EUR
BOSSBS-1123R-CY7
Anti-SEMA4C Rabbit Polyclonal Antibody (Cy7®)
Anticorpi
Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs) (By similarity). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: SEMA4C
Clonality: Polyclonal
Clone:
Conjugation: Cy7®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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