Anti-SDK1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Fornitore: Bioss
BOSSBS-11164R-A488EA 858 EUR
Anti-SDK1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Cell adhesion molecules influence cell growth, differentiation, embryogenesis, immune response and cancer metastasis by networking information from the extracellular matrix to the cell. Sidekick-1 (SDK1) is a 2,213 amino acid single-pass membrane protein that functions as a cell adhesion molecule by guiding axonal terminals to specific synapses in developing neurons. Existing as three alternatively spliced isoforms, Sidekick-1 is expressed in retinal neurons and contains thirteen fibronectin type-III domains and six Ig-like C2-type (immunoglobulin-like) domains. Sidekick-1 expression is upregulated in glomeruli of patients with HIV-associated nephropathy, where it leads to podocyte dysfunction. The gene encoding Sidekick-1 maps to human chromosome 7p22.2 and murine chromosome 5 G2.

Recommended Dilutions: Flow Cytometry: 1:20-100; IF(IHC-P): 1:50-200

Type: Primary
Antigen: SDK1
Clonality: Polyclonal
Conjugation: Alexa Fluor® 488
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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