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Anti-PCDHB12 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Fornitore: Bioss
BOSSBS-11153R-A555EA 858 EUR
BOSSBS-11153R-A555
Anti-PCDHB12 Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Anticorpi
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB12 (Protocadherin beta 12) is a 795 amino acid protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB12) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB12 is a single-pass type I membrane protein that contains six cadherin domains. PCDHB12 may participate in the establishment and maintenance of specific neuronal connections in the brain.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: PCDHB12
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
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