Stampa…

Anti-LMNB2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Fornitore: Bioss
BOSSBS-11132R-FITCEA 858 EUR
BOSSBS-11132R-FITC
Anti-LMNB2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
Anticorpi
A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: LMNB2
Clonality: Polyclonal
Clone:
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
Visualizza i codici

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Informazioni About VWR