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Anti-DYNC1I1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Fornitore: Bioss
BOSSBS-10470R-A488EA 858 EUR
BOSSBS-10470R-A488
Anti-DYNC1I1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)
Anticorpi
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: DYNC1I1
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 488
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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