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Anti-ADRA1B Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Fornitore: Bioss
BOSSBS-10465R-A647EA 858 EUR
BOSSBS-10465R-A647
Anti-ADRA1B Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Anticorpi
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq, Jul 2008].

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: ADRA1B
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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