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Anti-GNPTAB Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Fornitore: Bioss
BOSSBS-10460R-A555EA 858 EUR
BOSSBS-10460R-A555
Anti-GNPTAB Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Anticorpi
This gene encodes two of three subunit types of the membrane-bound enzyme N-acetylglucosamine-1-phosphotransferase, a heterohexameric complex composed of two alpha, two beta, and two gamma subunits. The encoded protein is proteolytically cleaved at the Lys928-Asp929 bond to yield mature alpha and beta polypeptides while the gamma subunits are the product of a distinct gene (GeneID 84572). In the Golgi apparatus, the heterohexameric complex catalyzes the first step in the synthesis of mannose 6-phosphate recognition markers on certain oligosaccharides of newly synthesized lysosomal enzymes. These recognition markers are essential for appropriate trafficking of lysosomal enzymes. Mutations in this gene have been associated with both mucolipidosis II and mucolipidosis IIIA.[provided by RefSeq, May 2010].

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: GNPTAB
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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