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Anti-TNFRSF11B Rabbit Polyclonal Antibody (Cy3®)

Fornitore: Bioss
BOSSBS-0431R-CY3EA 866 EUR
BOSSBS-0431R-CY3
Anti-TNFRSF11B Rabbit Polyclonal Antibody (Cy3®)
Anticorpi
Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF1/TRAIL and protect against apoptosis. TNFSF1/TRAIL binding blocks the inhibition of osteoclastogenesis.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: TNFRSF11B
Clonality: Polyclonal
Clone:
Conjugation: Cy3®
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat
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