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Anti-CDKN1A Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Fornitore: Bioss
BOSSBS-0741R-A555EA 866 EUR
BOSSBS-0741R-A555
Anti-CDKN1A Rabbit Polyclonal Antibody (Alexa Fluor® 555)
Anticorpi
May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity).

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: CDKN1A
Clonality: Polyclonal
Clone: 0
Conjugation: Alexa Fluor® 555
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity:
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