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Anti-ANGPT2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Fornitore: Bioss
BOSSBS-0677R-A647EA 866 EUR
BOSSBS-0677R-A647
Anti-ANGPT2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)
Anticorpi
Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: ANGPT2
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 647
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Pig
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