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Anti-ABCA1 Rabbit Polyclonal Antibody

Fornitore: Thermo Fisher Scientific
PIEAPA116789EA 0 EUR
PIEAPA116789
Anti-ABCA1 Rabbit Polyclonal Antibody
Anticorpi
ABCA1 is known to aggregate. DO NOT BOIL SAMPLES. Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking. ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.

Type: Primary
Antigen: ABCA1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Hamster, Canine, Chicken, Human, Mustelid, Rat, Porcine, Mouse
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