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Anti-53BP1 Rabbit Polyclonal Antibody

Fornitore: Thermo Fisher Scientific
PIEAPA116566EA 0 EUR
PIEAPA116566
Anti-53BP1 Rabbit Polyclonal Antibody
Anticorpi
Human samples have been tested in Western Blot and ICC/IF, and mouse samples have been tested in ICC/IF only. Suggested positive control: U205, 293T, and MO59K cell lysates and MEF lysates . P53-binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double-strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.

Type: Primary
Antigen: 53BP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Rat, Mouse, Human
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